TM4SF1 anticorps (N-Term)

N° du produit ABIN6991504

Détail du produit anti-TM4SF1 anticorps

Antigène: TM4SF1 (Transmembrane 4 L Six Family Member 1 (TM4SF1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TM4SF1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: At least three isoforms of TM4SF1 are known to exist, this antibody will recognize only the two largest isoforms. TM4SF1 antibody is predicted to not cross-react with other tetraspanin proteins.

Purification: TM4SF1 Antibody is affinity chromatography purified via peptide column.

Immunogène: TM4SF1 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human TM4SF1. The immunogen is located within the first 50 amino acids of TM4SF1.

Isotype: IgG

Information d'application

Indications d'application: TM4SF1 antibody can be used for detection of TM4SF1 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TM4SF1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TM4SF1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TM4SF1

Antigène: TM4SF1 (Transmembrane 4 L Six Family Member 1 (TM4SF1))

Autre désignation: TM4SF1 (TM4SF1 Produits)

Synonymes: anticorps MGC85546, anticorps h-l6, anticorps m3s1, anticorps taal6, anticorps H-L6, anticorps L6, anticorps M3S1, anticorps TAAL6, anticorps MM3, anticorps M3s1, anticorps transmembrane 4 L six family member 1, anticorps transmembrane 4 L six family member 1 S homeolog, anticorps transmembrane 4 superfamily member 1, anticorps TM4SF1, anticorps tm4sf1.S, anticorps tm4sf1, anticorps Tm4sf1

Sujet: TM4SF1 Antibody: TM4SF1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TM4SF1 is a cell surface antigen and is highly expressed in the vascular endothelium of several human cancers. Knockdown experiments of TM4SF1 prevented filopodia formation, inhibited cell mobility, blocked cytokinesis, and inhibited maturation of VEGF-A-induced angiogenesis, suggesting that TM4SF1 may be an attractive target for anti-angiogenesis therapy.

ID gène: 4071

NCBI Accession: NP_055035

UniProt: P30408