CD48 anticorps (AA 90-140)

N° du produit ABIN6991511

L’anticorps Lapin Polyclonal anti-CD48 a été validé pour WB et ELISA. Il convient pour détecter CD48 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CD48 anticorps (AA 90-140) (ABIN6991511)

Antigène: CD48

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD48 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CD48 anticorps

Épitope: AA 90-140

Specificité: Two isoforms of SLAMF2 are known to exist, this antibody will recognize both isoforms. SLAMF2 antibody is predicted to not cross-react with other SLAM protein family members.

Purification: SLAMF2 Antibody is affinity chromatography purified via peptide column.

Immunogène: SLAMF2 antibody was raised against a 19 amino acid synthetic peptide near the center of human SLAMF2. The immunogen is located within amino acids 90 - 140 of SLAMF2.

Isotype: IgG

Information d'application

Indications d'application: SLAMF2 antibody can be used for detection of SLAMF2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SLAMF2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SLAMF2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CD48

Antigène: CD48

Autre désignation: SLAMF2

Sujet: SLAMF2 Antibody: The signaling lymphocyte-activation molecule family member 2 (SLAMF2), also known as CD48, is a GPI-anchored protein that exists as both a soluble and membrane-associated form and is expressed in almost all leukocyte populations particularly in mitogen-stimulated human lymphocytes. SLAMF2 is a high-affinity ligand for SLAMF4, also known as 2B4, as well as a low-affinity ligand for CD2, and can thus can stimulate cells expressing these receptors. It has been shown to be an IL-3-induced activating receptor on eosinophils and is likely to be involved in promoting allergic inflammation. SLAMF2 is also thought to be involved in the IL-18/IL-18R signaling cascade in T and natural killer cells to produce interferon-gamma.

ID gène: 962

NCBI Accession: NP_1769

UniProt: P09326