LY9 anticorps (C-Term)

N° du produit ABIN6991512

Détail du produit anti-LY9 anticorps

Antigène: LY9 (CD229) (Lymphocyte Antigen 9 (CD229))

Épitope: AA 520-570, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LY9 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), ELISA, Immunofluorescence (IF)

Specificité: At least three isoforms of SLAMF3 are known to exist. SLAMF3 antibody is predicted to not cross-react with other SLAM protein family members.

Purification: SLAMF3 Antibody is affinity chromatography purified via peptide column.

Immunogène: SLAMF3 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SLAMF3. The immunogen is located within amino acids 520 - 570 of SLAMF3.

Isotype: IgG

Information d'application

Indications d'application: SLAMF3 antibody can be used for detection of SLAMF3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SLAMF3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SLAMF3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur LY9

Antigène: LY9 (CD229) (Lymphocyte Antigen 9 (CD229))

Autre désignation: SLAMF3 (CD229 Produits)

Synonymes: anticorps LY9, anticorps CD229, anticorps SLAMF3, anticorps hly9, anticorps mLY9, anticorps AI893573, anticorps Lgp100, anticorps Ly-9, anticorps T100, anticorps lymphocyte antigen 9, anticorps LY9, anticorps Ly9

Sujet: SLAMF3 Antibody: The signaling lymphocyte-activation molecule family member 3 (SLAMF3), also known as LY9, is a cell surface receptor that is expressed on T and B lymphocytes and belongs to the CD150/SLAMF1 receptor family. SLAMF3 was identified through a yeast two-hybrid screening in which SLAMF3 bound to the X-linked lymphoproliferative disease gene product SAP, suggesting that in activated T cells, SLAMF3 signaling can be triggered SAP. Its expression on the cell surface appears to be regulated via its interaction with the clathrin-associated adaptor complex 2 (AP-2). Despite its similarity to SLAMF1 in structure and interactions with SAP, SLAMF3-deficient mice do not exhibit phenotypic characteristics associated with SLAMF1- and SAP-deficient mice, suggesting that SLAMF3 plays other roles in T cell activation.

ID gène: 4063

NCBI Accession: NP_1769

UniProt: Q9HBG7

Pathways: BCR Signaling