CCDC141 anticorps (N-Term)

N° du produit ABIN6991553

L’anticorps anti-CCDC141 Polyclonal Lapin est utilisé pour la détection de CCDC141 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA, IF et IHC (p).

Aperçu rapide pour CCDC141 anticorps (N-Term) (ABIN6991553)

Antigène: CCDC141 (Coiled-Coil Domain Containing 141 (CCDC141))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCDC141 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CCDC141 anticorps

Épitope: AA 40-90, N-Term

Specificité: At least four isoforms of CCDC141 are known to exist.

Purification: CCDC141 Antibody is affinity chromatography purified via peptide column.

Immunogène: CCDC141 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CCDC141. The immunogen is located within amino acids 40 - 90 of CCDC141.

Isotype: IgG

Information d'application

Indications d'application: CCDC141 antibody can be used for detection of CCDC141 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CCDC141 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CCDC141 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CCDC141

Antigène: CCDC141 (Coiled-Coil Domain Containing 141 (CCDC141))

Autre désignation: CCDC141

Sujet: CCDC141 Antibody: Coiled-coil domain-containing protein 141 (CCDC141), also known as CAMDI, is a recently identified disrupted in schizophrenia 1 (DISC1)-binding protein that also associates with myosin II. CCDC141 preferentially associates with phosphomyosin II and causes an accumulation of phosphomyosin II at the centrosome in a DISC1-dependent manner. Knockdown of CCDC141 expression by RNAi led to severely impaired radial migration with disoriented chromosomes, suggesting that CCDC141 is required for radial migration through DISC1 and myosin II-mediated centrosome positioning during neuronal development.

ID gène: 285025

NCBI Accession: NP_775919

UniProt: Q6ZP82