CMYA5 anticorps (C-Term)

N° du produit ABIN6991554

Détail du produit anti-CMYA5 anticorps

Antigène: CMYA5 (Cardiomyopathy Associated 5 (CMYA5))

Épitope: AA 3810-3860, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CMYA5 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: SPRYD2 antibody is predicted to not cross-react with other SPRYD protein family members. At least four isoforms of SPRYD2 are known to exist.

Purification: SPRYD2 Antibody is affinity chromatography purified via peptide column.

Immunogène: SPRYD2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SPRYD2. The immunogen is located within amino acids 3810 - 3860 of SPRYD2.

Isotype: IgG

Information d'application

Indications d'application: SPRYD2 antibody can be used for detection of SPRYD2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SPRYD2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SPRYD2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CMYA5

Antigène: CMYA5 (Cardiomyopathy Associated 5 (CMYA5))

Autre désignation: SPRYD2 (CMYA5 Produits)

Synonymes: anticorps cmya5l, anticorps DKFZp469P2126, anticorps C5orf10, anticorps SPRYD2, anticorps TRIM76, anticorps 2310076E16Rik, anticorps 2310076E21Rik, anticorps AA420382, anticorps AI504003, anticorps Srfsd, anticorps Tims, anticorps sr553, anticorps cardiomyopathy associated 5, anticorps CMYA5, anticorps cmya5, anticorps Cmya5

Sujet: SPRYD2 Antibody: SPRYD2, also known as Myospryn, was originally identified as the muscle-specific partner of dysbindin and as a Mef-2 target gene. It is a large scaffolding protein localized to the Z-disc/costamere region of striated muscle. SPRYD2 includes a noncanonical tripartite motif (TRIM-like) that lacks the RING domain but consists of a B-box coiled coil (BBC), fibronectin 3 (FN3) repeats, and SPRY domains. SPRYD2 interacts with desmin and calcineurin, and it has been suggested to play a role in the biogenesis of lysosome and negatively regulates slow-fiber-type transformation and skeletal muscle regeneration. SPRYD2 is dysregulated in Duchenne muscular dystrophy.

ID gène: 202333

NCBI Accession: NP_705838

UniProt: Q8N3K9