Ly6k anticorps (N-Term)

N° du produit ABIN6991564

Cet anticorps Lapin Polyclonal détecte spécifiquement Ly6k dans ELISA et WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Ly6k anticorps (N-Term) (ABIN6991564)

Antigène: Ly6k (Lymphocyte Antigen 6 Complex, Locus K (Ly6k))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ly6k est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-Ly6k anticorps

Épitope: N-Term

Specificité: Multiple isoforms of LY6K are known to exist.

Purification: LY6K Antibody is affinity chromatography purified via peptide column.

Immunogène: LY6K antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human LY6K. The immunogen is located within the first 50 amino acids of LY6K.

Isotype: IgG

Information d'application

Indications d'application: LY6K antibody can be used for detection of LY6K by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: LY6K Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: LY6K antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur Ly6k

Antigène: Ly6k (Lymphocyte Antigen 6 Complex, Locus K (Ly6k))

Autre désignation: LY6K

Sujet: LY6K Antibody: The lymphocyte antigen 6 complex locus K (LY6K), a member of cancer-testis antigen was initially identified as a molecular marker for head-and-neck squamous cell carcinoma as well a breast cancer. LY6K is a GPI-anchored membrane protein that is specifically associated with germ cell marker TEX101 and is strongly observed in testis, but only weakly in other tissues. LY6K mRNA was found to be upregulated in numerous bladder cancers due to gene amplification. Furthermore, knockdown experiments using LY6K siRNA reduced cell growth, migration and invasion in bladder carcinoma cell lines, suggesting that LY6K contributes to bladder cancer development.

ID gène: 54742

UniProt: Q17RY6