CHD7 anticorps (N-Term)

N° du produit ABIN6991566

Détail du produit anti-CHD7 anticorps

Antigène: CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))

Épitope: AA 670-720, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHD7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: Multiple isoforms of CHD7 are known to exist.

Purification: CHD7 Antibody is affinity chromatography purified via peptide column.

Immunogène: CHD7 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CHD7. The immunogen is located within amino acids 670 - 720 of CHD7.

Isotype: IgG

Information d'application

Indications d'application: CHD7 antibody can be used for detection of CHD7 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CHD7 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CHD7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CHD7

Antigène: CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))

Autre désignation: CHD7 (CHD7 Produits)

Synonymes: anticorps CHD7, anticorps fd19h06, anticorps si:ch211-197o6.2, anticorps wu:cegs2051, anticorps wu:fb37f10, anticorps wu:fb39h04, anticorps wu:fd19h06, anticorps HH5, anticorps IS3, anticorps KAL5, anticorps A730019I05Rik, anticorps Cycn, anticorps Cyn, anticorps Dz, anticorps Edy, anticorps Flo, anticorps GENA 47, anticorps GENA 60, anticorps Gena 52, anticorps Lda, anticorps Mt, anticorps Obt, anticorps Todo, anticorps WBE1, anticorps Whi, anticorps metis, anticorps chromodomain helicase DNA binding protein 7 L homeolog, anticorps chromodomain helicase DNA binding protein 7, anticorps chd7.L, anticorps CHD7, anticorps chd7, anticorps Chd7

Sujet: CHD7 Antibody: CHD proteins belong to a superfamily of proteins of ATP-dependent chromatin remodeling enzymes that have a unique combination of functional domains, including two N-terminal chromodomains, a SNF2-like ATPase/helicase domain and a DNA-binding domain. These proteins are thought to play a role in early embryonic development by affecting chromatin structure and gene expression. Mutations in one member of this family, CHD7, result in CHARGE syndrome. It colocalizes with embryonic stem (ES) cell master regulators OCT4/POU5F1, SOX2, and NANOG and is thought to modulate ES-specific gene transcription. Together with SOX2, CHD7 has been suggested to also regulate several human disease genes.

ID gène: 55636

UniProt: Q9P2D1

Pathways: Sensory Perception of Sound, Chromatin Binding