DRAXIN anticorps (C-Term)

N° du produit ABIN6991584

Cet anticorps anti-DRAXIN Polyclonal Lapin (ABIN6991584) détecte spécifiquement DRAXIN dans WB, ELISA, IHC (p) et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour DRAXIN anticorps (C-Term) (ABIN6991584)

Antigène: DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DRAXIN est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-DRAXIN anticorps

Épitope: C-Term

Specificité: At least three isoforms of Neucrin are known to exist, this antibody will detect the two shorter isoforms. Neucrin antibody is predicted to not cross-react with RILP.

Purification: NEUCRIN Antibody is affinity chromatography purified via peptide column.

Immunogène: Neucrin antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human Neucrin. The immunogen is located within the last 50 amino acids of NEUCRIN.

Isotype: IgG

Information d'application

Indications d'application: Neucrin antibody can be used for detection of Neucrin by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: NEUCRIN Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: NEUCRIN antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur DRAXIN

Antigène: DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))

Autre désignation: NEUCRIN

Sujet: NEUCRIN Antibody: Neucrin, also known as Draxin, is a repulsive guidance protein for the spinal cord and forebrain commissures. It is thought to act as an antagonist of canonical Wnt signaling by inhibiting the stabilization of cytosolic beta-catenin. Ectopically expressed neucrin inhibited growth or caused misrouting of chick spinal cord commissural axons in vivo while Neucrin-null mice showed defasciculation of spinal cord commissural axons and an absence of all forebrain commisures. Other experiments in mice have shown that olfactory bulb axonal outgrowth is inhibited by Neucrin, suggesting that Neucrin functions as an inhibitory guidance cue for olfactory bulb axons.

ID gène: 374946

UniProt: Q8NBI3