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PIWIL2 anticorps (AA 410-460)

PIWIL2 Reactivité: Humain, Souris WB, ELISA, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6991609
  • Antigène Voir toutes PIWIL2 Anticorps
    PIWIL2 (Piwi-Like 2 (PIWIL2))
    Épitope
    • 14
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 410-460
    Reactivité
    • 30
    • 10
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 31
    • 3
    • 1
    Lapin
    Clonalité
    • 33
    • 2
    Polyclonal
    Conjugué
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PIWIL2 est non-conjugé
    Application
    • 25
    • 16
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    At least three isoforms of PIWI-L2 are known to exist, this antibody will only detect the two longest isoforms. PIWI-L2 antibody is predicted to not cross-react with other PIWI protein family members.
    Purification
    PIWI-L2 Antibody is affinity chromatography purified via peptide column.
    Immunogène
    PIWI-L2 antibody was raised against a 17 amino acid synthetic peptide near the center of human PIWI-L2. The immunogen is located within amino acids 410 - 460 of PIWI-L2.
    Isotype
    IgG
    Top Product
    Discover our top product PIWIL2 Anticorps primaire
  • Indications d'application
    PIWI-L2 antibody can be used for detection of PIWI-L2 by Western blot at 1 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PIWI-L2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    PIWI-L2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    PIWIL2 (Piwi-Like 2 (PIWIL2))
    Autre désignation
    PIWI-L2 (PIWIL2 Produits)
    Synonymes
    anticorps si:dkey-88f5.1, anticorps zili, anticorps Piwil1l, anticorps mili, anticorps CT80, anticorps HILI, anticorps PIWIL1L, anticorps piwil2, anticorps piwi like RNA-mediated gene silencing 2, anticorps piwi-like RNA-mediated gene silencing 2, anticorps piwil2, anticorps Piwil2, anticorps PIWIL2
    Sujet
    PIWI-L2 Antibody: PIWI-L2 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. PIWI-L2 has been implicated in multiple roles including stem cell self-renewal and is highly expressed in many breast cancers. In these tumors, PIWI-L2 silences the expression of STAT3, a regulator of Bcl-XL and cyclin D1, allowing the proliferation and survival of breast cancer stem cells. Recent studies have shown that overexpression of PIWI-like proteins are potential biomarkers for colon and other cancers.
    ID gène
    55124
    NCBI Accession
    NP_00129193
    UniProt
    Q8TC59
    Pathways
    Stem Cell Maintenance
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