SIK3 anticorps (C-Term)

N° du produit ABIN6991618

Cet anticorps Poulet Polyclonal détecte spécifiquement SIK3 dans ELISA, WB et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour SIK3 anticorps (C-Term) (ABIN6991618)

Antigène: SIK3 (SIK Family Kinase 3 (SIK3))

Reactivité: Humain, Souris, Rat

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp SIK3 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-SIK3 anticorps

Épitope: AA 1190-1240, C-Term

Specificité: At least three isoforms of SIK3 are known to exist, this antibody will detect two isoforms. SIK3 antibody is predicted to not cross-react with SIK1 and SIK2.

Purification: SIK3 Antibody is affinity chromatography purified via peptide column.

Immunogène: SIK3 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SIK3. The immunogen is located within amino acids 1190 - 1240 of SIK3.

Isotype: IgY

Information d'application

Indications d'application: SIK3 antibody can be used for detection of SIK3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SIK3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SIK3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SIK3

Antigène: SIK3 (SIK Family Kinase 3 (SIK3))

Autre désignation: SIK3

Sujet: SIK3 Antibody: Salt-inducible kinase family (SIKs) proteins are thought to have a role in steroidogenesis, adipogenesis or regulation of tumor malignancy. Three members (SIK1, SIK2 and SIK3) in the SIK family have been identified thus far. Their kinase domain sequences are closely homologous to those of AMP-activated protein kinase (AMPK). SIK3 can be phosphorylated by a tumor-suppressor kinase LKB1. It is highly and preferentially expressed in ovarian tumors but not in adenomyosis and leiomyoma and may be a potential diagnostic marker for ovarian cancers.

ID gène: 23387

NCBI Accession: NP_079440

UniProt: Q9Y2K2