SIPA1 anticorps (N-Term)

N° du produit ABIN6991630

Détail du produit anti-SIPA1 anticorps

Antigène: SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))

Épitope: AA 40-90, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIPA1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Specificité: At least three isoforms of SIPA1 are known to exist, this antibody will recognize all three isoforms. This antibody is specific for SIPA1 and will not recognize the other SIPA1 family of proteins.

Purification: SIPA1 Antibody is affinity chromatography purified via peptide column.

Immunogène: SIPA1 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human SIPA1. The immunogen is located within amino acids 40 - 90 of SIPA1.

Isotype: IgG

Information d'application

Indications d'application: SIPA1 antibody can be used for detection of EPAC1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SIPA1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SIPA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SIPA1

Antigène: SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))

Autre désignation: SIPA1 (SIPA1 Produits)

Synonymes: anticorps Spa1, anticorps SPA1, anticorps signal-induced proliferation-associated 1, anticorps Signal peptidase I (leader peptidase I), anticorps signal-induced proliferation associated gene 1, anticorps SIPA1, anticorps sipA1, anticorps Sipa1

Sujet: SIPA1 Antibody: Signal-induced proliferation 1 (SIPA1) is a member of the SIPA1 family of RapGAPs, a family of mitogen-induced GTPase activating proteins. SIPA1 exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. When abnormally or prematurely expressed, SIPA1 may also hamper mitogen-induced cell cycle progression and may increase metastases in human cancers.

ID gène: 6494

UniProt: Q96FS4

Pathways: Response to Water Deprivation