CASKIN2 anticorps (N-Term)

N° du produit ABIN6991638

Détail du produit anti-CASKIN2 anticorps

Antigène: CASKIN2 (CASK Interacting Protein 2 (CASKIN2))

Épitope: AA 380-430, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CASKIN2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: CASKIN2 antibody is predicted to not cross-react with other CASKIN family members. Three isoforms of CASKIN2 are known to exist, this antibody will not detect the shortest isoform.

Purification: CASKIN2 Antibody is affinity chromatography purified via peptide column.

Immunogène: CASKIN2 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human CASKIN2. The immunogen is located within amino acids 380 - 430 of CASKIN2.

Isotype: IgG

Information d'application

Indications d'application: CASKIN2 antibody can be used for detection of EPAC1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CASKIN2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CASKIN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CASKIN2

Antigène: CASKIN2 (CASK Interacting Protein 2 (CASKIN2))

Autre désignation: CASKIN2 (CASKIN2 Produits)

Synonymes: anticorps anks5b, anticorps MGC98998, anticorps ANKS5B, anticorps 1600028L06Rik, anticorps mKIAA1139, anticorps CASK interacting protein 2, anticorps cask-interacting protein 2, anticorps CASK interacting protein 2 L homeolog, anticorps CASK-interacting protein 2, anticorps CASKIN2, anticorps Caskin2, anticorps caskin2.L

Sujet: CASKIN2 Antibody: Calcium/calmodulin-dependent serine protein kinase (CASK) is a conserved multi-domain scaffolding protein involved in brain development, synapse formation, and establishment of cell polarity. CASKINs (CASK interacting protein ) interact with CASK and is thought to play a role in CASK function, specifically by coupling CASK to distinct downstream effectors. CASKIN2 is a multidomain protein containing six N-terminal ankyrin repeats, one SH3 domain, and two sterile alpha motif domains followed by a long proline-rich sequence and a short conserved C-terminal domain. It is expressed ubiquitously with highest levels present in fetal and adult liver tissue.

Poids moléculaire: Predicted: 123, 132 kDa

Observed: 120 kDa

ID gène: 57513

NCBI Accession: NP_065804

UniProt: Q8WXE0