B9D1 anticorps (C-Term)
Aperçu rapide pour B9D1 anticorps (C-Term) (ABIN6991647)
Antigène
Voir toutes B9D1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 130-180, C-Term
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Specificité
- At least two isoforms of B9D1 are known to exist, this antibody will only recognize the longest isoform. B9D1 antibody is predicted to not cross-react with other DNAJC family members.
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Purification
- B9D1 Antibody is affinity chromatography purified via peptide column.
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Immunogène
- B9D1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human B9D1. The immunogen is located within amino acids 130 - 180 of B9D1.
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Isotype
- IgG
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Indications d'application
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B9D1 antibody can be used for detection of B9D1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- B9D1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,4 °C
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Stockage commentaire
- B9D1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- B9D1 (B9 Protein Domain 1 (B9D1))
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Autre désignation
- B9D1
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Sujet
- B9D1 Antibody: Meckel syndrome (MKS) is an embryonic lethal, autosomal recessive disorder characterized by polycystic kidney disease, central nervous system defects, polydactyly and liver fibrosis. B9D1 is a B9 domain-containing protein, one of several that are involved in ciliogenesis. Alterations in expression of this gene have been found in a family with Meckel syndrome. B9D1, and its related protein B9D2, form a complex with MKS1, disruption of which causes MKS. B9D1 is thought to be required for normal hedgehog signaling, ciliogenesis, and ciliary protein localization.
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ID gène
- 27077
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NCBI Accession
- NP_056496
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UniProt
- Q9UPM9
Antigène
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