MLIP anticorps (C-Term)

N° du produit ABIN6991648

Cet anticorps Lapin Polyclonal détecte spécifiquement MLIP dans WB, ELISA, IHC (p) et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour MLIP anticorps (C-Term) (ABIN6991648)

Antigène: MLIP (Muscular LMNA-Interacting Protein (MLIP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLIP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-MLIP anticorps

Épitope: C-Term

Specificité: At least three isoforms of MLIP are known to exist.

Purification: MLIP Antibody is affinity chromatography purified via peptide column.

Immunogène: MLIP antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human MLIP. The immunogen is located within the last 50 amino acids of MLIP.

Isotype: IgG

Information d'application

Indications d'application: MLIP antibody can be used for detection of MLIP by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: MLIP Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: MLIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur MLIP

Antigène: MLIP (Muscular LMNA-Interacting Protein (MLIP))

Autre désignation: MLIP

Sujet: MLIP Antibody: The muscle-enriched A-type lamin-interacting protein (MLIP) is ubiquitously expressed, although most predominantly in heart, skeletal and smooth muscle, and interacts directly and co-localizes with lamin A and C in the nuclear envelope. MLIP also co-localizes with promyelocytic leukemia (PML) bodies within the nucleus. Decreasing lamin A/C expression with siRNA results in the upregulation and mislocalization of MLIP, suggesting that MLIP localization to the nuclear envelope is dependent on the lamin proteins. It has been suggested that MLIP may function as a tethering protein linking LMNA to factors within the nuclear envelope of within PML bodies

ID gène: 90523

NCBI Accession: NP_612636

UniProt: Q5VWP3