C9ORF116 anticorps (N-Term)

N° du produit ABIN6991649

L’anticorps anti-C9ORF116 Polyclonal Lapin est utilisé pour la détection de C9ORF116 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA et ICC.

Aperçu rapide pour C9ORF116 anticorps (N-Term) (ABIN6991649)

Antigène: C9ORF116 (Chromosome 9 Open Reading Frame 116 (C9ORF116))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C9ORF116 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Détail du produit anti-C9ORF116 anticorps

Épitope: N-Term

Specificité: PIERCE1 antibody is predicted to not cross-react with other UPF0691 family members.

Purification: PIERCE1 Antibody is affinity chromatography purified via peptide column.

Immunogène: PIERCE1 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human PIERCE1. The immunogen is located within the first 50 amino acids of PIERCE1.

Isotype: IgG

Information d'application

Indications d'application: PIERCE1 antibody can be used for detection of PIERCE1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PIERCE1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: PIERCE1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur C9ORF116

Antigène: C9ORF116 (Chromosome 9 Open Reading Frame 116 (C9ORF116))

Autre désignation: PIERCE1

Sujet: PIERCE1 Antibody: PIERCE1, also known as C9orf116, is an important p53 target gene contributing to normal DNA damage response and may play crucial roles in maintaining genomic integrity against genotoxic stresses, including UVC irradiation. PIERCE1 exists as two alternatively spliced isoforms and is predominantly expressed in human small cell lung cancer. PIERCE1 knockdown induces down-regulation of proapoptotic genes including Ei24, Apaf1 and PTEN, suggesting that PIERCE1 is a proapoptotic gene. It is helpful for in-depth understanding of p53 pathways and the design of new cancer therapies.

ID gène: 138162

UniProt: Q5BN46