Nkx2-2 anticorps (AA 90-140)

N° du produit ABIN6991653

Cet anticorps anti-Nkx2-2 est un anticorps Lapin Polyclonal détectant Nkx2-2 dans IF, IHC (p), WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Nkx2-2 anticorps (AA 90-140) (ABIN6991653)

Antigène: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nkx2-2 est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), ELISA

Détail du produit anti-Nkx2-2 anticorps

Épitope: AA 90-140

Specificité: NKX2-2 antibody is predicted to not cross-react with other NK2 homeobox family members.

Purification: NKX2-2 Antibody is affinity chromatography purified via peptide column.

Immunogène: NKX2-2 antibody was raised against a 19 amino acid synthetic peptide near the center of human NKX2-2. The immunogen is located within amino acids 90 - 140 of NKX2-2.

Isotype: IgG

Information d'application

Indications d'application: NKX2-2 antibody can be used for detection of NKX2-2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: NKX2-2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: NKX2-2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur Nkx2-2

Antigène: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Autre désignation: NKX2-2

Sujet: NKX2-2 Antibody: NKX2-2 (NK2 homeobox 2) is a member of a family of transcription factors that are involved in embryonic development and cell fate. NKX2-2 is crucial in the development of pancreatic islet cell differentiation and activates the ghrelin-promoter in these cells. NKX2-2 is expressed at the onset of pancreatic epithelium formation and becomes restricted to mature α,-, β,- and PP cells, and in NKX2-2-null mice embryos, all β,-cells and most a-cells are replaced by ghrelin-positive cells. NKX2-2 is also thought to be involved in ventral neuronal patterning and floor plate development and commissural axon guidance.

ID gène: 4821

NCBI Accession: NP_002500

UniProt: O95096

Pathways: Dopaminergic Neurogenesis