YPEL3 anticorps (N-Term)

N° du produit ABIN6991665

Cet anticorps anti-YPEL3 est un anticorps Lapin Polyclonal détectant YPEL3 dans ELISA, WB, IF et ICC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour YPEL3 anticorps (N-Term) (ABIN6991665)

Antigène: YPEL3 (Yippee-Like 3 (YPEL3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YPEL3 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-YPEL3 anticorps

Épitope: AA 20-70, N-Term

Purification: YPEL3 Antibody is affinity chromatography purified via peptide column.

Immunogène: YPEL3 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human YPEL3. The immunogen is located within amino acids 20 - 70 of YPEL3.

Isotype: IgG

Information d'application

Indications d'application: YPEL3 antibody can be used for detection of YPEL3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 2.5 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: YPEL3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: YPEL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur YPEL3

Antigène: YPEL3 (Yippee-Like 3 (YPEL3))

Autre désignation: YPEL3

Sujet: YPEL3 Antibody: YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors.

ID gène: 83719

NCBI Accession: NP_113665

UniProt: P61236