RAB21 anticorps (C-Term)

N° du produit ABIN6991713

Cet anticorps anti-RAB21 est un anticorps Lapin Polyclonal détectant RAB21 dans WB, ELISA et IF. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour RAB21 anticorps (C-Term) (ABIN6991713)

Antigène: RAB21 (RAB21, Member RAS Oncogene Family (RAB21))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB21 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-RAB21 anticorps

Épitope: C-Term

Specificité: This antibody is predicted to not cross-react with other Ras-related proteins

Purification: RAB21 Antibody is affinity chromatography purified via peptide column.

Immunogène: RAB21 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human RAB21. The immunogen is located within the last 50 amino acids of RAB21.

Isotype: IgG

Information d'application

Indications d'application: RAB21 antibody can be used for detection of RAB21 by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: RAB21 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: RAB21 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur RAB21

Antigène: RAB21 (RAB21, Member RAS Oncogene Family (RAB21))

Autre désignation: RAB21

Sujet: RAB21 Antibody: RAB21 is a member of a subfamily of small GTP-binding protein genes of the Ras superfamily that plays an important role in intracellular vesicular targeting. In non-polarized Caco-2 cells, RAB21 showed a general endoplasmic reticulum (ER)-like localization, while in polarized cells, RAB21 localized to apical vesicles. RAB21 has been shown to associate with integrin subunits and to be important for receptor entry into cells via RAB5/RAB21 endosomes. The GTPase-activating protein p120RasGAP regulates cell motility by controlling the return of the endocytosed integrins to the plasma membrane by competing with RAB21 for binding to overlapping sites on the α,-tail of endocytosed integrin.

ID gène: 23011

NCBI Accession: NP_055814

UniProt: Q9UL25