ANG anticorps (AA 70-120)

N° du produit ABIN6991733

Détail du produit anti-ANG anticorps

Antigène: ANG (Angiogenin (ANG))

Épitope: AA 70-120

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANG est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificité: Two alternatively spliced transcript variants have been observed.

Purification: ANG Antibody is affinity chromatography purified via peptide column.

Immunogène: ANG antibody was raised against a 15 amino acid synthetic peptide near the center of human ANG. The immunogen is located within amino acids 70 - 120 of ANG.

Isotype: IgG

Information d'application

Indications d'application: ANG antibody can be used for detection of ANG by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: ANG Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: ANG antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ANG

Antigène: ANG (Angiogenin (ANG))

Autre désignation: ANG (ANG Produits)

Synonymes: anticorps ALS9, anticorps HEL168, anticorps RNASE4, anticorps RNASE5, anticorps ANG, anticorps AI385586, anticorps Ang1, anticorps Rnase5, anticorps Rnase5a, anticorps ANG1, anticorps angiogenin, anticorps angiogenin, ribonuclease, RNase A family, 5, anticorps ribonuclease A family member k6, anticorps ANG, anticorps Ang, anticorps RNASE6

Sujet: ANG Antibody: Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin is a genetic link between ALS and PD.

Poids moléculaire: 16 kDa

ID gène: 283

NCBI Accession: NP_001136

UniProt: P03950