BCL6 anticorps (AA 370-420)
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- Antigène Voir toutes BCL6 Anticorps
- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
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Épitope
- AA 370-420
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BCL6 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- Three alternatively spliced transcript variants have been observed
- Purification
- BCL6 Antibody is affinity chromatography purified via peptide column.
- Immunogène
- BCL6 antibody was raised against an 18 amino acid synthetic peptide near the center of human BCL6. The immunogen is located within amino acids 370 - 420 of BCL6.
- Isotype
- IgG
- Top Product
- Discover our top product BCL6 Anticorps primaire
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- Indications d'application
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BCL6 antibody can be used for detection of BCL6 by Western blot at 1 μ,g/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- BCL6 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- BCL6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
- Autre désignation
- BCL6 (BCL6 Produits)
- Synonymes
- anticorps bcl5, anticorps laz3, anticorps bcl6a, anticorps znf51, anticorps zbtb27, anticorps MGC132260, anticorps Bcl5, anticorps BCL5, anticorps BCL6A, anticorps LAZ3, anticorps ZBTB27, anticorps ZNF51, anticorps B-cell CLL/lymphoma 6 L homeolog, anticorps B-cell CLL/lymphoma 6, anticorps B cell leukemia/lymphoma 6, anticorps bcl6.L, anticorps bcl6, anticorps BCL6, anticorps Bcl6
- Sujet
- BCL6 Antibody: BCL6 was first identified as a proto-oncogene in diffuse large B cell lymphoma. BCL6, a transcriptional repressor, plays an important role in lymphomagenesis. It binds Stat recognition-like DNA elements and is required for affinity maturation of mature B cells in germinal centers and Th1/Th2 differentiation, a process that critically depends on BCL6-mediated transcriptional repression of p53. BCL6 is a pharmacological target for eradication of leukemia-initiating cells in chronic myeloid leukemia (CML).
- Poids moléculaire
- 78 kDa
- ID gène
- 604
- NCBI Accession
- NP_001124317
- UniProt
- P41182
- Pathways
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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