Myc Target 1 anticorps (C-Term)

N° du produit ABIN6991752

Cet anticorps anti-Myc Target 1 est un anticorps Lapin Polyclonal détectant Myc Target 1 dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Myc Target 1 anticorps (C-Term) (ABIN6991752)

Antigène: Myc Target 1 (MYCT1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Myc Target 1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Myc Target 1 anticorps

Épitope: C-Term

Specificité: At least two isoforms of MYCT1 are known to exist, this antibody will detect both isoforms.

Purification: MYCT1 Antibody is affinity chromatography purified via peptide column.

Immunogène: MYCT1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human MYCT1. The immunogen is located within the last 50 amino acids of MYCT1.

Isotype: IgG

Information d'application

Indications d'application: MYCT1 antibody can be used for detection of MYCT1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: MYCT1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: MYCT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur Myc Target 1

Antigène: Myc Target 1 (MYCT1)

Autre désignation: MYCT1

Sujet: MYCT1 Antibody: MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.

Poids moléculaire: 26 kDa

ID gène: 80177

NCBI Accession: NP_079383

UniProt: Q8N699