PLA1A anticorps (C-Term)
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- Antigène Voir toutes PLA1A Anticorps
- PLA1A (Phospholipase A1 Member A (PLA1A))
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Épitope
- AA 380-430, C-Term
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Reactivité
- Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PLA1A est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Specificité
- At least three isoforms of PLA1A are known to exist, this antibody will detect all three isoforms.
- Purification
- PLA1A Antibody is affinity chromatography purified via peptide column.
- Immunogène
- PLA1A antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human PLA1A. The immunogen is located within amino acids 380 - 430 of PLA1A.
- Isotype
- IgG
- Top Product
- Discover our top product PLA1A Anticorps primaire
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- Indications d'application
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PLA1A antibody can be used for detection of PLA1A by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PLA1A Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- PLA1A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- PLA1A (Phospholipase A1 Member A (PLA1A))
- Autre désignation
- PLA1A (PLA1A Produits)
- Synonymes
- anticorps PS-PLA1, anticorps PSPLA1, anticorps AA986889, anticorps Ps-pla1, anticorps Pspla1, anticorps wu:fi26h09, anticorps zgc:77160, anticorps AH, anticorps ARWH2, anticorps LAH2, anticorps LPDLR, anticorps PLA1B, anticorps mPA-PLA1, anticorps phospholipase A1 member A, anticorps lipase H, anticorps PLA1A, anticorps Pla1a, anticorps pla1a, anticorps CpipJ_CPIJ002492, anticorps CpipJ_CPIJ007883, anticorps LIPH
- Sujet
- PLA1A Antibody: PLA1A is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine (PS) in liposomes and can also hydrolyze PS in apoptotic cells and activate platelets where the resulting 2-acyl-lysophosphatidylserine acts as a lipid mediator for mast cells, T cells, and neural cells, suggesting that a major function of PLA1A may be the production of lysophospholipid mediators. PLA1A is upregulated in rat peripheral blood cells bearing long-term surviving cardiac allograft. PLA1A is also expressed in human THP-1-derived macrophages and this expression is upregulated in cells treated with lipopolysaccharide, a TLR4 ligand. This upregulation is inhibited with corticosteroids, which are often used at high dosages to suppress chronic allograft rejection.
- Poids moléculaire
- 50 kDa
- ID gène
- 51365
- NCBI Accession
- NP_056984
- UniProt
- Q53H76
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