PANX1 anticorps (N-Term)

N° du produit ABIN6991780

Cet anticorps Lapin Polyclonal détecte spécifiquement PANX1 dans WB, ELISA et IF. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour PANX1 anticorps (N-Term) (ABIN6991780)

Antigène: PANX1 (Pannexin 1 (PANX1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PANX1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-PANX1 anticorps

Épitope: AA 70-120, N-Term

Specificité: Two transcript variants encoding different isoforms have been found for this gene.

Purification: PANX1 Antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal PANX1 antibody was raised against a 17 amino acid peptide near the amino terminus of human PANX1. The immunogen is located within amino acids 70 - 120 of PANX1.

Isotype: IgG

Information d'application

Indications d'application: PANX1 antibody can be used for detection of PANX1 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PANX1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: PANX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PANX1

Antigène: PANX1 (Pannexin 1 (PANX1))

Autre désignation: PANX1

Sujet: PANX1 Antibody: The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.

Poids moléculaire: 47 kDa

ID gène: 24145

NCBI Accession: NP_056183

UniProt: Q96RD7