SHROOM1 anticorps (C-Term)

N° du produit ABIN6991786

Cet anticorps Lapin Polyclonal détecte spécifiquement SHROOM1 dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour SHROOM1 anticorps (C-Term) (ABIN6991786)

Antigène: SHROOM1 (Shroom Family Member 1 (SHROOM1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHROOM1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-SHROOM1 anticorps

Épitope: C-Term

Specificité: SHROOM1 antibody is human, mouse and rat reactive. At least three isoforms of SHROOM1 are known to exist, this antibody will detect only the two largest isoforms. SHROOM1 antibody is predicted to not cross-react with other SHROOM family members.

Purification: SHROOM1 Antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal SHROOM1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human SHROOM1. The immunogen is located within the last 50 amino acids of SHROOM1.

Isotype: IgG

Information d'application

Indications d'application: SHROOM1 antibody can be used for detection of SHROOM1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SHROOM1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SHROOM1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SHROOM1

Antigène: SHROOM1 (Shroom Family Member 1 (SHROOM1))

Autre désignation: SHROOM1

Sujet: SHROOM1 Antibody: SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM1 is a PDZ domain-containing actin-binding protein that is required for neural tube morphogenesis. It facilitates neurulation by regulating the morphology of neurepithelial cells via the apical positioning of an actomyosin network in the neurepithelium. SHROOM1 is also expressed in pulmonary arterial smooth muscle cells and its expression is significantly decreased in mouse and human models of pulmonary arterial hypertension, suggesting that there may be a link between SHROOM1 expression and pulmonary arterial hypertension.

Poids moléculaire: 94 kDa

ID gène: 134549

NCBI Accession: NP_001166171

UniProt: Q2M3G4