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TSPY1L (C-Term) anticorps

Reactivité: Humain, Souris ELISA, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6991788
  • Antigène
    TSPY1L
    Épitope
    C-Term
    Reactivité
    Humain, Souris
    Hôte
    Lapin
    Clonalité
    Polyclonal
    Application
    ELISA, Western Blotting (WB)
    Specificité
    TSPY1L antibody is human and mouse reactive. At least three isoforms of TSPY1 are known to exist, this antibody will detect only TSPY1L.
    Purification
    TSPY1L Antibody is affinity chromatography purified via peptide column.
    Immunogène
    Rabbit polyclonal TSPY1L antibody was raised against a 20 amino acid peptide near the carboxy terminus of human TSPY1L. The immunogen is located within the last 50 amino acids of TSPY1L.
    Isotype
    IgG
  • Indications d'application
    TSPY1L antibody can be used for detection of TSPY1L by Western blot at 0.5 - 1 μ,g/mL.

    Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    TSPY1L Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    TSPY1L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    TSPY1L
    Sujet
    TSPY1L Antibody: Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.
    Poids moléculaire
    34 kDa
    ID gène
    7258
    NCBI Accession
    NP_003299
    UniProt
    Q01534
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