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TSPY1S (C-Term) anticorps

Cet anticorps Lapin Polyclonal détecte spécifiquement dans ELISA et WB. Il présente une réactivité envers Humain et Souris.
N° du produit ABIN6991789

Aperçu rapide pour TSPY1S (C-Term) anticorps (ABIN6991789)

Antigène

TSPY1S

Reactivité

Humain, Souris

Hôte

Lapin

Clonalité

Polyclonal

Application

ELISA, Western Blotting (WB)
  • Épitope

    C-Term

    Specificité

    TSPY1S antibody is human and mouse reactive. At least three isoforms of TSPY1 are known to exist, this antibody will detect only TSPY1S

    Purification

    TSPY1S Antibody is affinity chromatography purified via peptide column.

    Immunogène

    Rabbit polyclonal TSPY1S antibody was raised against a 13 amino acid peptide near the carboxy terminus of human TSPY1S. The immunogen is located within the last 50 amino acids of TSPY1S.

    Isotype

    IgG
  • Indications d'application

    TSPY1S antibody can be used for detection of TSPY1S by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    TSPY1S Antibody is supplied in PBS containing 0.02 % sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C,4 °C

    Stockage commentaire

    TSPY1S antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène

    TSPY1S

    Sujet

    TSPY1S Antibody: Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.

    Poids moléculaire

    32 kDa

    ID gène

    7258

    NCBI Accession

    NP_001184171

    UniProt

    Q01534
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