TSPY1S (C-Term) anticorps

N° du produit ABIN6991789

Détail du produit

Antigène: TSPY1S

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Application: ELISA, Western Blotting (WB)

Specificité: TSPY1S antibody is human and mouse reactive. At least three isoforms of TSPY1 are known to exist, this antibody will detect only TSPY1S

Purification: TSPY1S Antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal TSPY1S antibody was raised against a 13 amino acid peptide near the carboxy terminus of human TSPY1S. The immunogen is located within the last 50 amino acids of TSPY1S.

Isotype: IgG

Information d'application

Indications d'application: TSPY1S antibody can be used for detection of TSPY1S by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TSPY1S Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TSPY1S antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détail du antigène

Antigène: TSPY1S

Sujet: TSPY1S Antibody: Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.

Poids moléculaire: 32 kDa

ID gène: 7258

NCBI Accession: NP_001184171

UniProt: Q01534