DHX36 anticorps (C-Term)

N° du produit ABIN6991798

Cet anticorps Lapin Polyclonal détecte spécifiquement DHX36 dans WB, ELISA et IHC (p). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour DHX36 anticorps (C-Term) (ABIN6991798)

Antigène: DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DHX36 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-DHX36 anticorps

Épitope: C-Term

Specificité: At least four isoforms of DDX36 are known to exist, this antibody will detect the three longest isoforms.

Purification: DHX36 Antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal DHX36 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human DHX36. The immunogen is located within the last 50 amino acids of DHX36.

Isotype: IgG

Information d'application

Indications d'application: DHX36 antibody can be used for detection of DHX36 by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: DHX36 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: DHX36 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur DHX36

Antigène: DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))

Autre désignation: DHX36

Sujet: DHX36 Antibody: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure. DHX36 (DEAH box protein 36), also known as MLE-like protein 1 and RNA helicase associated with AU-rich element ARE (RHAU), belongs to RNA helicase of the DEAH family and may function in sex development and spermatogenesis. It is expressed in testis and is evolutionary conserved with true orthologs in almost all animal species. DHX36 plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. DHX36 is required for early embryogenesis.

Poids moléculaire: Predicted: 111 kDa

ID gène: 170506

NCBI Accession: NP_065916

UniProt: Q9H2U1

Pathways: Toll-Like Receptors Cascades