CARM1 anticorps (N-Term)

N° du produit ABIN6991814

L’anticorps anti-CARM1 Polyclonal Lapin est utilisé pour la détection de CARM1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et IF.

Aperçu rapide pour CARM1 anticorps (N-Term) (ABIN6991814)

Antigène: CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CARM1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-CARM1 anticorps

Épitope: AA 470-520, N-Term

Purification: CARM1 Antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal CARM1 antibody was raised against a 19 amino acid peptide near the amino terminus of human CARM1. The immunogen is located within amino acids 470 - 520 of CARM1.

Isotype: IgG

Information d'application

Indications d'application: CARM1 antibody can be used for detection of CARM1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CARM1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CARM1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur CARM1

Antigène: CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))

Autre désignation: CARM1

Sujet: CARM1 Antibody: Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation. CARM1 functions as a transcriptional co-activator for various nuclear receptors and NF-κ,B. It has also been shown to methylate histone H3 arginines, inhibiting the binding of corepressors and protecting chromatin from deacetylation, thereby facilitating transcription.

Poids moléculaire: Predicted: 67 kDa

ID gène: 10498

NCBI Accession: NP_954592

UniProt: Q86X55

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation