SDPR anticorps (N-Term)

N° du produit ABIN6991833

Cet anticorps anti-SDPR est un anticorps Lapin Polyclonal détectant SDPR dans WB, ELISA, IHC (p) et IF. Adapté pour Humain.

Aperçu rapide pour SDPR anticorps (N-Term) (ABIN6991833)

Antigène: SDPR (Serum Deprivation Response (SDPR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SDPR est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-SDPR anticorps

Épitope: N-Term

Specificité: It is predicted to not cross-react with other members of the cavin family.

Purification: SDPR Antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal SDPR antibody was raised against an 18 amino acid peptide near the amino terminus of human SDPR. The immunogen is located within the first 50 amino acids of SDPR.

Isotype: IgG

Information d'application

Indications d'application: SDPR antibody can be used for detection of SDPR by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SDPR Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SDPR antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur SDPR

Antigène: SDPR (Serum Deprivation Response (SDPR))

Autre désignation: SDPR

Sujet: SDPR Antibody: The serum deprivation-response protein (SDPR) is a calcium-independent phospholipid-binding protein whose expression is increased in serum-starved cells. SDPR is a substrate for protein kinase C (PKC) phosphorylation and recruits the polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. Both SDPR and PTRF, as well as the other member of the cavin family PRKCDBP were down regulated in breast cancer cell lines and breast tumor tissue, suggesting that expression of the cavin family proteins could be a useful prognostic indicator of breast cancer progression.

Poids moléculaire: Predicted: 22, 33, 43 kDa kDa

Observed: 30 kDa

ID gène: 8436

NCBI Accession: NP_004648

UniProt: O95810