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SHISA3 anticorps (AA 120-170)

SHISA3 Reactivité: Souris, Humain, Rat WB, ELISA, IHC (p), IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6991837
  • Antigène Voir toutes SHISA3 Anticorps
    SHISA3 (Shisa Homolog 3 (SHISA3))
    Épitope
    • 8
    • 8
    • 7
    AA 120-170
    Reactivité
    Souris, Humain, Rat
    Hôte
    • 15
    Lapin
    Clonalité
    • 15
    Polyclonal
    Conjugué
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp SHISA3 est non-conjugé
    Application
    • 15
    • 13
    • 12
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Specificité
    SHISA3 antibody is predicted to not cross-react with other SHISA protein family members.
    Purification
    SHISA3 Antibody is affinity chromatography purified via peptide column.
    Immunogène
    SHISA3 antibody was raised against a 15 amino acid peptide near the center of human SHISA3 . The immunogen is located within amino acids 120 - 170 of SHISA3.
    Isotype
    IgG
    Top Product
    Discover our top product SHISA3 Anticorps primaire
  • Indications d'application
    SHISA3 Antibody can be used for detection of SHISA3 by Western blot at 1 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    SHISA3 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    SHISA3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Antigène
    SHISA3 (Shisa Homolog 3 (SHISA3))
    Autre désignation
    SHISA3 (SHISA3 Produits)
    Synonymes
    anticorps hShisa3, anticorps D830007B15Rik, anticorps shisa family member 3, anticorps SHISA3, anticorps Shisa3
    Sujet
    SHISA3 Antibody: SHISA3 plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling. The Shisa family of single-transmembrane proteins is characterized by an N-terminal cysteine-rich domain and a proline-rich C-terminal region. Its founding member, Xenopus Shisa, promotes head development by antagonizing Wnt and FGF signaling. Shisa physically interacted with immature forms of the Wnt receptor Frizzled and the FGF receptor within the ER and inhibited their posttranslational maturation and trafficking to the cell surface. Loss of Shisa function sensitized the neuroectoderm to Wnt signaling and suppressed head formation during gastrulation.
    Poids moléculaire
    Predicted: 26 kDa

    Observed: 28 kDa
    ID gène
    152573
    NCBI Accession
    NP_001073974
    UniProt
    A0PJX4
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