C1orf64 anticorps (C-Term)

N° du produit ABIN6991843

Cet anticorps Lapin Polyclonal détecte spécifiquement C1orf64 dans ELISA, WB, IHC (p) et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour C1orf64 anticorps (C-Term) (ABIN6991843)

Antigène: C1orf64 (C1ORF64) (Chromosome 1 Open Reading Frame 64 (C1ORF64))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C1orf64 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-C1orf64 anticorps

Épitope: C-Term

Purification: ERRF Antibody is affinity chromatography purified via peptide column.

Immunogène: ERRF antibody was raised against a 15 amino acid peptide near the carboxy terminus of human ERRF . The immunogen is located within the last 50 amino acids of ERRF.

Isotype: IgG

Information d'application

Indications d'application: ERRF Antibody can be used for detection of ERRF by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human and mouse samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: ERRF Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: ERRF antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur C1orf64

Antigène: C1orf64 (C1ORF64) (Chromosome 1 Open Reading Frame 64 (C1ORF64))

Autre désignation: ERRF

Sujet: ERRF Antibody: The estrogen receptor-related factor (ERRF) is a recently identified protein whose expression is upregulated in multiple cell lines and primary breast cancer tumors. Increased ERRF expression was significantly associated with ER or progesterone receptor (PR) positivity even in HER2-negative tumors. This higher ERRF expression correlated with better disease-free survival and overall survival. In two ER-positive breast cancer cell lines, knockdown of ERRF suppressed cell growth in vitro and tumorigenesis in xenograft models, suggesting that ERRF plays a role in estrogen-ER-mediated breast cancer cell growth and may thus be a potential therapeutic target.

Poids moléculaire: Predicted: 19 kDa

Observed: 15 kDa

ID gène: 149563

NCBI Accession: NP_849162

UniProt: Q8NEQ6