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WAC anticorps (AA 210-260)

WAC Reactivité: Humain, Souris, Rat ELISA, WB, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6991845
  • Antigène Voir toutes WAC Anticorps
    WAC (WW Domain Containing Adaptor with Coiled-Coil (WAC))
    Épitope
    • 7
    • 7
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 210-260
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 22
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    Cet anticorp WAC est non-conjugé
    Application
    • 17
    • 17
    • 13
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    At least two isoforms of WAC are known to exist, this antibody will detect the larger isoform.
    Purification
    WAC Antibody is affinity chromatography purified via peptide column.
    Immunogène
    WAC antibody was raised against a 19 amino acid peptide near the center of human WAC . The immunogen is located within amino acids 210 - 260 of WAC.
    Isotype
    IgG
    Top Product
    Discover our top product WAC Anticorps primaire
  • Indications d'application
    WAC Antibody can be used for detection of WAC by Western blot at 1 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    WAC Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    WAC antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Antigène
    WAC (WW Domain Containing Adaptor with Coiled-Coil (WAC))
    Autre désignation
    WAC (WAC Produits)
    Synonymes
    anticorps BM-016, anticorps PRO1741, anticorps Wwp4, anticorps 1110067P07Rik, anticorps A230035H12Rik, anticorps AI256735, anticorps AI256776, anticorps DKFZp468H162, anticorps wac, anticorps wu:fc13f04, anticorps wu:fj68f01, anticorps zgc:55755, anticorps RGD1562407, anticorps zgc:101828, anticorps WW domain containing adaptor with coiled-coil, anticorps WW domain containing adaptor with coiled-coil a, anticorps WW domain containing adaptor with coiled-coil b, anticorps WAC, anticorps Wac, anticorps wac, anticorps waca, anticorps wacb
    Sujet
    WAC Antibody: The WW domain containing adaptor with coiled-coil protein (WAC) contains a WW domain that mediates protein-protein interactions and colocalizes with RNA splicing factor SC35. Further studies have indicated that WAC is a functional partner of the RNF20/40 complex that ubiquitinates Histone H2B, and that WAC regulates H2B ubiquitination. WAC targets RNF20/40 to associate with RNA polymerase II complex for H2B ubiquitination at active transcription sites. WAC-dependent transcription is also important for cell-cycle checkpoint activation in response to genotoxic stress.
    Poids moléculaire
    Predicted: 71 kDa

    Observed: 75 kDa
    ID gène
    51322
    NCBI Accession
    NP_057712
    UniProt
    Q9BTA9
    Pathways
    Chromatin Binding
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