ULK2 anticorps (AA 480-530)

N° du produit ABIN6991859

L’anticorps Lapin Polyclonal anti-ULK2 a été validé pour WB, ELISA, IHC (p) et IF. Il convient pour détecter ULK2 dans des échantillons de Humain.

Aperçu rapide pour ULK2 anticorps (AA 480-530) (ABIN6991859)

Antigène: ULK2 (Unc-51 Like Kinase 2 (ULK2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ULK2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-ULK2 anticorps

Épitope: AA 480-530

Specificité: At least two isoforms of ULK2 are known to exist, this antibody will detect both isoforms. ULK2 antibody is predicted to not cross-react with ULK1.

Purification: ULK2 Antibody is affinity chromatography purified via peptide column.

Immunogène: ULK2 antibody was raised against a 17 amino acid peptide near the center of human ULK2 . The immunogen is located within amino acids 480 - 530 of ULK2.

Isotype: IgG

Information d'application

Indications d'application: ULK2 Antibody can be used for detection of ULK2 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: ULK2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: ULK2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur ULK2

Antigène: ULK2 (Unc-51 Like Kinase 2 (ULK2))

Autre désignation: ULK2

Sujet: ULK2 Antibody: ULK2, also known as ATG1B, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK2 results in a severe defect in the autophagy pathway. ULK2 is highly conserved among eukaryotes and shows high homology with its related protein ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200 that mediates TOR signaling and is essential for autophagy. Like ULK1, ULK2 is also thought to be involved in early neuronal growth and differentiation.

Poids moléculaire: Predicted: 105, 114 kDa

Observed: 100 kDa

ID gène: 9706

NCBI Accession: NP_055498

UniProt: Q8IYT8

Pathways: Regulation of Cell Size, Autophagy