GABARAP anticorps (N-Term)

N° du produit ABIN6991865

L’anticorps Lapin Polyclonal anti-GABARAP a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter GABARAP dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GABARAP anticorps (N-Term) (ABIN6991865)

Antigène: GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GABARAP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GABARAP anticorps

Épitope: N-Term

Specificité: Multiple isoforms of GABARAP exist due to alternative splicing events.

Purification: GABARAP Antibody is affinity chromatography purified via peptide column.

Immunogène: GABARAP antibody was raised against a 19 amino acid peptide near the amino terminus of human GABARAP. The immunogen is located within the first 50 amino acids of GABARAP.

Isotype: IgG

Information d'application

Indications d'application: GABARAP antibody can be used for detection of GABARAP by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: GABARAP Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: GABARAP antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur GABARAP

Antigène: GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

Autre désignation: GABARAP

Sujet: GABARAP Antibody: Gamma-aminobutyric acid (GABA) is the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing in the central nervous system. It has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. GABARAP (GABAA receptor-associated protein) links GABAA receptors to the cytoskeleton and may play a role in intracellular transport of GABAA receptors and its interaction with the cytoskeleton. GABARAP belongs to the MAP1 or ATG8 like family and recent studies show that MAPK15/ERK8 is acting through interaction with ATG8 family proteins to regulate autophagy.

Poids moléculaire: Predicted: 13kDa

Observed: 15 kDa

ID gène: 11337

NCBI Accession: NP_009209

UniProt: O95166

Pathways: Autophagy