TLX3 anticorps (N-Term)

N° du produit ABIN6991868

L’anticorps Lapin Polyclonal anti-TLX3 a été validé pour WB, ELISA, IHC (p) et IF. Il convient pour détecter TLX3 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TLX3 anticorps (N-Term) (ABIN6991868)

Antigène: TLX3 (T-Cell Leukemia Homeobox 3 (TLX3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLX3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-TLX3 anticorps

Épitope: N-Term

Specificité: TLX3 antibody is predicted to not cross-react with other TLX proteins.

Purification: TLX3 Antibody is affinity chromatography purified via peptide column.

Immunogène: TLX3 antibody was raised against a 16 amino acid peptide near the amino terminus of human TLX3. The immunogen is located within the first 50 amino acids of TLX3.

Isotype: IgG

Information d'application

Indications d'application: TLX3 antibody can be used for detection of TLX3 by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TLX3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TLX3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur TLX3

Antigène: TLX3 (T-Cell Leukemia Homeobox 3 (TLX3))

Autre désignation: TLX3

Sujet: TLX3 Antibody: The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX3, also known as homeobox11-like1 (HOX11L2), is a DNA-binding nuclear transcription factor that is expressed in a subset of the primary sensory nervous system. TLX3, along with the related TLX1, is a selector transcription factor that promotes an excitatory glutamatergic neuronal phenotype over an inhibitory GABAergic phenotype opposing LBX1 signals during dorsal spinal cord development. Chromosomal translocations of the TLX3 gene have been shown to result in some forms of T-cell acute lymphoblastic leukemia (T-ALL).

Poids moléculaire: Predicted: 32 kDa

Observed: 30 kDa

ID gène: 30012

NCBI Accession: NP_066305

UniProt: O43711