DAP anticorps (C-Term)
-
- Antigène Voir toutes DAP Anticorps
- DAP (Death-Associated Protein (DAP))
-
Épitope
- C-Term
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp DAP est non-conjugé
-
Application
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- DAP antibody is human, mouse and rat reactive.
- Purification
- DAP Antibody is affinity chromatography purified via peptide column.
- Immunogène
- DAP antibody was raised against a 19 amino acid peptide near the carboxy terminus of human DAP. The immunogen is located within the last 50 amino acids of DAP.
- Isotype
- IgG
- Top Product
- Discover our top product DAP Anticorps primaire
-
-
- Indications d'application
-
DAP antibody can be used for detection of DAP by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- DAP Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- DAP antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
- Antigène
- DAP (Death-Associated Protein (DAP))
- Autre désignation
- DAP (DAP Produits)
- Synonymes
- anticorps Rap7a, anticorps 4921531N22Rik, anticorps AI789753, anticorps AU040360, anticorps MGC53808, anticorps MGC85522, anticorps DAP1, anticorps DAP, anticorps Dap, anticorps ACYPI007535, anticorps DAP-1, anticorps dap1a, anticorps wu:fa16h08, anticorps wu:fc06d11, anticorps death associated protein, anticorps death-associated protein, anticorps death-associated protein S homeolog, anticorps DAP, anticorps Dap, anticorps dap.S, anticorps dap
- Sujet
- DAP Antibody: The Death-associated protein (DAP) is a basic proline-rich 15 kDa protein that as a positive mediator of programmed cell death that is induced by interferon-gamma (1). DAP is also a direct substrate of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Under rich nutrient conditions, mTOR phosphorylates DAP at Ser3 and Ser51, under starvation conditions, these residues are dephosphorylated and DAP is converted into an active suppressor of autophagy (2).
- Poids moléculaire
-
Predicted: 11 kDa
Observed: 11 kDa - ID gène
- 1611
- NCBI Accession
- NP_004385
- UniProt
- P51397
- Pathways
- Positive Regulation of Endopeptidase Activity, Feeding Behaviour
-