DDC anticorps (C-Term)

N° du produit ABIN6991892

L’anticorps Lapin Polyclonal anti-DDC a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter DDC dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour DDC anticorps (C-Term) (ABIN6991892)

Antigène: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDC est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-DDC anticorps

Épitope: AA 390-440, C-Term

Specificité: DDC antibody is human, mouse and rat reactive.

Purification: DDC Antibody is affinity chromatography purified via peptide column.

Immunogène: DDC antibody was raised against a 14 amino acid peptide near the carboxy terminus of human DDC. The immunogen is located within amino acids 390 - 440 of DDC .

Isotype: IgG

Information d'application

Indications d'application: DDC antibody can be used for detection of DDC by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: DDC Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: DDC antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur DDC

Antigène: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Autre désignation: DDC

Sujet: DOPA decarboxylase (DDC) belongs to the group II decarboxylase family of proteins (1). It is an important protein in the catecholamine biosynthesis pathway. DDC catalyzes the second reaction in the biosynthesis of catecholamines, trace amines and serotonin (1,2). It can form a homodimer and is expressed in the central nervous system (2). DDC can be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease, neuroendocrine tumors and drug abuse (3,4). Defects in DDC gene may cause the autosomal recessive disorder AADC deficiency (4).

Poids moléculaire: Predicted: 53 kDa

Observed: 53 kDa

ID gène: 1644

NCBI Accession: NP_000781

UniProt: P20711

Pathways: Dopaminergic Neurogenesis