FLI1 anticorps (C-Term)

N° du produit ABIN6991893

Cet anticorps anti-FLI1 est un anticorps Lapin Polyclonal détectant FLI1 dans WB, ELISA et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour FLI1 anticorps (C-Term) (ABIN6991893)

Antigène: FLI1 (Friend Leukemia Virus Integration 1 (FLI1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FLI1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-FLI1 anticorps

Épitope: C-Term

Specificité: FLI1 antibody is human, mouse and rat reactive. At least four isoforms of FLI1 are known to exist, this antibody will detect all four.

Purification: FLI1 Antibody is affinity chromatography purified via peptide column.

Immunogène: FLI1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human FLI1. The immunogen is located within the last 50 amino acids of FLI1 .

Isotype: IgG

Information d'application

Indications d'application: FLI1 antibody can be used for detection of FLI1 by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: FLI1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: FLI1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur FLI1

Antigène: FLI1 (Friend Leukemia Virus Integration 1 (FLI1))

Autre désignation: FLI1

Sujet: The Friend leukemia virus integration 1 (FLI1) protein is a transcription factor containing an ETS DNA-binding domain and is highly expressed in hematopoietic cell lineages and vascular endothelial cells (1). FLI1 plays important roles in megakaryocytic differentiation (2) and vascular homeostasis (3). The FLI1 gene can undergo a t(11,22)(q24,q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. (4). Abnormal expression of FLI1 can be used as an adverse prognostic indicator for acute myeloid leukemia (5).

Poids moléculaire: Predicted: 50 kDa

Observed: 52kDa

ID gène: 2313

NCBI Accession: NP_002008

UniProt: Q01543