Arylsulfatase B anticorps (C-Term)

N° du produit ABIN6991898

L’anticorps Lapin Polyclonal anti-Arylsulfatase B a été validé pour WB, ELISA, IHC (p) et IF. Il convient pour détecter Arylsulfatase B dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Arylsulfatase B anticorps (C-Term) (ABIN6991898)

Antigène: Arylsulfatase B (ARSB)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Arylsulfatase B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-Arylsulfatase B anticorps

Épitope: AA 460-510, C-Term

Specificité: ARSB antibody is human, mouse and rat reactive. At least two isoforms of ARSB are known to exist, this antibody only recognizes the longest isoform.

Purification: ARSB Antibody is affinity chromatography purified via peptide column.

Immunogène: ARSB antibody was raised against a 16 amino acid peptide near the carboxy terminus of human ARSB. The immunogen is located within amino acids 460 - 510 of ARSB .

Isotype: IgG

Information d'application

Indications d'application: ARSB antibody can be used for detection of ARSB by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: ARSB Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: ARSB antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur Arylsulfatase B

Antigène: Arylsulfatase B (ARSB)

Autre désignation: ARSB

Sujet: Aryl sulfatase B (ARSB) forms a homodimer that hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate (1). ARSB localizes to the lysozyme as well as to the extracellular matrix (2). Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B (3), and can be treated with exogenous ARSB (4).

Poids moléculaire: Predicted: 59 kDa

Observed: 57kDa

ID gène: 411

NCBI Accession: NP_000037

UniProt: P15848

Pathways: Glycosaminoglycan Metabolic Process