ERAP2 anticorps (N-Term)

N° du produit ABIN6991900

Cet anticorps Lapin Polyclonal détecte spécifiquement ERAP2 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour ERAP2 anticorps (N-Term) (ABIN6991900)

Antigène: ERAP2 (Endoplasmic Reticulum Aminopeptidase 2 (ERAP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERAP2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ERAP2 anticorps

Épitope: AA 110-160, N-Term

Specificité: ERAP2 antibody is human reactive. Multiple isoforms of ERAP2 are known to exist. ERAP2 antibody is predicted to not cross-react with ERAP1.

Purification: ERAP2 Antibody is affinity chromatography purified via peptide column.

Immunogène: ERAP2 antibody was raised against a 17 amino acid peptide near the amino terminus of human ERAP2. The immunogen is located within amino acids 110 - 160 of ERAP2 .

Isotype: IgG

Information d'application

Indications d'application: ERAP2 antibody can be used for detection of ERAP2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: ERAP2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: ERAP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur ERAP2

Antigène: ERAP2 (Endoplasmic Reticulum Aminopeptidase 2 (ERAP2))

Autre désignation: ERAP2

Sujet: The endoplasmic reticulum (ER) aminopeptidase 2 (ERAP2), a member of the peptidase M1 family, like the related protein ERAP1, plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides (1,2). Like ERAP1, ERAP2 is localized to the lumen of the ER and is thought to associate with ERAP1 as a heterodimer (1). Both ERAP1 and ERAP2 have been linked to several human diseases ranging from infections to autoimmunity and cancer, and may play a role in the innate immune response (reviewed in 3).

Poids moléculaire: Predicted: 106 kDa

Observed: 120kDa

ID gène: 64167

NCBI Accession: NP_071745

UniProt: Q6P179