BTLA anticorps (AA 170-220)

N° du produit ABIN6991902

Cet anticorps anti-BTLA est un anticorps Lapin Polyclonal détectant BTLA dans WB, ELISA, IF et IHC (p). Adapté pour Humain.

Aperçu rapide pour BTLA anticorps (AA 170-220) (ABIN6991902)

Antigène: BTLA (B and T Lymphocyte Associated (BTLA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BTLA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-BTLA anticorps

Épitope: AA 170-220

Specificité: BTLA antibody is human specific. At least two isoforms of BTLA are known to exist.

Purification: BTLA Antibody is affinity chromatography purified via peptide column.

Immunogène: BTLA antibody was raised against a 17 amino acid peptide near the center of human BTLA. The immunogen is located within amino acids 170 - 220 of BTLA .

Isotype: IgG

Information d'application

Indications d'application: BTLA antibody can be used for detection of BTLA by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: BTLA Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: BTLA antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur BTLA

Antigène: BTLA (B and T Lymphocyte Associated (BTLA))

Autre désignation: BTLA

Sujet: The B- and T-lymphocyte attenuator (BTLA) protein is a member of the immunoglobulin superfamily containing a single immunoglobulin (Ig) domain (1). Like other coihibitory receptors such as CTLA-4 and PD-1, BTLA functions as a receptor that relays inhibitory signals to suppress the immune response, and can inhibit LPS-induced endotoxic shock by suppressing TLR4 signaling in innate immune cells (1,2). Polymorphisms in this gene have also been associated with an increased risk of rheumatoid arthritis (3).

Poids moléculaire: Predicted: 32 kDa

Observed: 40kDa

ID gène: 151888

NCBI Accession: NP_861445

UniProt: Q7Z6A9

Pathways: Cancer Immune Checkpoints