T-Bet anticorps (C-Term)

N° du produit ABIN6991904

Détail du produit anti-T-Bet anticorps

Antigène: T-Bet

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp T-Bet est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificité: TBX21 antibody is human and mouse reactive.

Purification: TBX21 Antibody is affinity chromatography purified via peptide column.

Immunogène: TBX21 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human TBX2. The immunogen is located within the last 50 amino acids of TBX21 .

Isotype: IgG

Information d'application

Indications d'application: TBX21 antibody can be used for detection of TBX21 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TBX21 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TBX21 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur T-Bet

Antigène: T-Bet

Autre désignation: TBX21 (T-Bet Produits)

Synonymes: anticorps T-PET, anticorps T-bet, anticorps TBET, anticorps TBLYM, anticorps TBT1, anticorps Tbet, anticorps Tblym, anticorps T-box 21, anticorps TBX21, anticorps Tbx21

Sujet: TBX21 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box (1,2). Members of this family include transcription factors involved in the regulation of developmental processes (2). Studies in mouse and humans show that TBX21 is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (1,3). Expression of the human ortholog also correlates with interferon-gamma expression in Th1 and natural killer cells, suggesting a TBX21 may play a role in initiating Th1 lineage development from naive Th precursor cells. (3).

Poids moléculaire: Predicted: 59 kDa

Observed: 55kDa

ID gène: 30009

NCBI Accession: NP_037483

UniProt: Q9UL17