SOGA1 anticorps (C-Term)

N° du produit ABIN6991908

Cet anticorps anti-SOGA1 Polyclonal Lapin (ABIN6991908) détecte spécifiquement SOGA1 dans WB, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour SOGA1 anticorps (C-Term) (ABIN6991908)

Antigène: SOGA1 (Suppressor of Glucose, Autophagy Associated 1 (SOGA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOGA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-SOGA1 anticorps

Épitope: C-Term

Specificité: SOGA1 antibody is human specific. At least four isoforms of SOGA1 are known to exist.

Purification: SOGA1 Antibody is affinity chromatography purified via peptide column.

Immunogène: SOGA1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human SOGA. The immunogen is located within the last 50 amino acids of SOGA1 .

Isotype: IgG

Information d'application

Indications d'application: SOGA1 antibody can be used for detection of SOGA1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SOGA1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SOGA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur SOGA1

Antigène: SOGA1 (Suppressor of Glucose, Autophagy Associated 1 (SOGA1))

Autre désignation: SOGA1

Sujet: The recently identified protein suppressor of glucose by autophagy protein 1 (SOGA1) has been found to be involved in the regulation of autophagy (1). SOGA1 is thought to contribute to adiponectin-mediated insulin-dependent inhibition of autophagy during the activation of adenosine monophosphate kinase (AMPK) (1,2). SOGA1 contains an internal signal peptide that enables the secretion of a circulating fragment of SOGA1, providing a surrogate marker for intracellular SOGA1 levels (2). Knockdown of SOGA1 elevated glucose production in primary hepatocytes indicates that SOGA1 is an inhibitor of glucose production. It thus might be useful as a novel therapeutic target for diabetes (3).

Poids moléculaire: Predicted: 183 kDa

Observed: 200kDa

ID gène: 140710

NCBI Accession: NP_954650

UniProt: O94964