FIL1d anticorps (C-Term)

N° du produit ABIN6991918

Cet anticorps Lapin Polyclonal détecte spécifiquement FIL1d dans WB, ELISA, IHC (p) et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour FIL1d anticorps (C-Term) (ABIN6991918)

Antigène: FIL1d (Interleukin 1 delta (FIL1d))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FIL1d est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-FIL1d anticorps

Épitope: C-Term

Specificité: IL-36RN antibody is human and mouse reactive. At least two isoforms of IL-36RN are known to exist

Purification: IL-36RN antibody is affinity chromatography purified via peptide column.

Immunogène: IL-36RN antibody was raised against a 19 amino acid peptide near the carboxy terminus of human IL-36RN. The immunogen is located within the last 50 amino acids of IL-36RN.

Isotype: IgG

Information d'application

Indications d'application: IL-36RN antibody can be used for detection of IL-36RN by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: IL-36RN antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: IL-36RN antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur FIL1d

Antigène: FIL1d (Interleukin 1 delta (FIL1d))

Autre désignation: IL-36RN

Sujet: IL-36RN is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36RN specifically inhibits the activation of NF-kappaB induced IL-36A (2). The opposing activities of these cytokines have been suggested to be involved in the regulation of skin inflammation (3). Like the IL-36 cytokines (IL-36A, IL-36B and IL-36G), IL-36RN requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (4).

Poids moléculaire: Observed Molecular Weight: 24 kDa

ID gène: 26525

NCBI Accession: NP_775262

UniProt: Q9UBH0