COMMD7 anticorps (AA 90-140)
Aperçu rapide pour COMMD7 anticorps (AA 90-140) (ABIN6991926)
Antigène
Voir toutes COMMD7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 90-140
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Specificité
- COMMD7 antibody is human, mouse and rat reactive. Multiple transcript variants encoding different isoforms have been found for COMMD7.
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Purification
- COMMD7 antibody is affinity chromatography purified via peptide column.
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Immunogène
- COMMD7 antibody was raised against a 19 amino acid peptide near the center of human COMMD7. The immunogen is located within amino acids 90 - 140 of COMMD7.
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Isotype
- IgG
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Indications d'application
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COMMD7 antibody can be used for detection of COMMD7 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- COMMD7 antibody is supplied in PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,4 °C
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Stockage commentaire
- COMMD7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- COMMD7 (COMM Domain Containing 7 (COMMD7))
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Autre désignation
- COMMD7
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Sujet
- COMMD7 (COMM domain-containing protein 7) plays a role in the regulation NF-kappaB (1). It associates with the NF-kB complex and suppresses its transcriptional activity (2). COMMD7 contains 1 COMM domain and widely expressed with highest expression in lung (3). COMMD7 is a newly identified gene overexpressed in hepatocellular carcinoma (HCC) (4). COMMD7 is associated with tumor invasion and poor prognosis by NF-kappaB signaling pathway (4).
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Poids moléculaire
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Predicted: 22 kDa
Observed: 21 kDa -
ID gène
- 149951
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NCBI Accession
- NP_444269
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UniProt
- Q86VX2
Antigène
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