Dynamin 1-Like anticorps (AA 530-580)

N° du produit ABIN6991941

Cet anticorps anti-Dynamin 1-Like est un anticorps Lapin Polyclonal détectant Dynamin 1-Like dans WB, ELISA, IF et ICC. Adapté pour Humain et Souris.

Aperçu rapide pour Dynamin 1-Like anticorps (AA 530-580) (ABIN6991941)

Antigène: Dynamin 1-Like (DNM1L)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dynamin 1-Like est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-Dynamin 1-Like anticorps

Épitope: AA 530-580

Specificité: DNM1L antibody is human and mouse reactive. At least four isoforms of DNM1L are known to exist, this antibody will detect the two longest isoforms.

Purification: DNM1L antibody is affinity chromatography purified via peptide column.

Immunogène: DNM1L antibody was raised against a 19 amino acid peptide near the center of human DNM1L. The immunogen is located within amino acids 530 - 580 of DNM1L.

Isotype: IgG

Information d'application

Indications d'application: DNM1L antibody can be used for detection of DNM1L by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: DNM1L antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: DNM1L antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur Dynamin 1-Like

Antigène: Dynamin 1-Like (DNM1L)

Autre désignation: DNM1L

Sujet: The Dynamin-1-like protein (DNM1L) is a member of the dynamin superfamily of GTPases (1). DNM1L mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis (2). Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF) (3).

Poids moléculaire: Predicted: 81 kDa

Observed: 80 kDa

ID gène: 10059

NCBI Accession: NP_036192

UniProt: O00429