RPSA/Laminin Receptor anticorps (C-Term)
Aperçu rapide pour RPSA/Laminin Receptor anticorps (C-Term) (ABIN6991942)
Antigène
Voir toutes RPSA/Laminin Receptor (RPSA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 190-240, C-Term
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Specificité
- RPSA antibody is human, mouse and rat reactive.
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Purification
- RPSA antibody is affinity chromatography purified via peptide column.
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Immunogène
- RPSA antibody was raised against a 17 amino acid peptide near the carboxy terminus of human RPSA. The immunogen is located within amino acids 190 - 240 of RPSA.
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Isotype
- IgG
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Indications d'application
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RPSA antibody can be used for detection of RPSA by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- RPSA antibody is supplied in PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,4 °C
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Stockage commentaire
- RPSA antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))
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Autre désignation
- RPSA
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Sujet
- The 40S ribosomal protein SA (RPSA) is a high-affinity, non-integrin family, laminin receptor, also known as 67 kDa laminin receptor or 37 kDa laminin receptor precursor (37LRP) (1). Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes and have been implicated in a variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis (2). RPSA is overexpressed in multiple types of cancers and has recently been shown to act as a cancer-specific death receptor (3).
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Poids moléculaire
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Predicted: 32 kDa
Observed: 32 kDa -
ID gène
- 3921
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NCBI Accession
- NP_002286
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UniProt
- P08865
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Pathways
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
Antigène
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