CXCR3 anticorps (C-Term)

N° du produit ABIN6991955

L’anticorps anti-CXCR3 Polyclonal Lapin est utilisé pour la détection de CXCR3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IF et ICC.

Aperçu rapide pour CXCR3 anticorps (C-Term) (ABIN6991955)

Antigène: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-CXCR3 anticorps

Épitope: C-Term

Specificité: CXCR3 antibody is human, mouse and rat reactive. At least two isoforms of CXCR3 are known to exist, this antibody will detect both isoforms.

Purification: CXCR3 antibody is affinity chromatography purified via peptide column.

Immunogène: CXCR3 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human CXCR3 . The immunogen is located within the last 50 amino acids of CXCR3.

Isotype: IgG

Information d'application

Indications d'application: CXCR3 antibody can be used for detection of CXCR3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CXCR3 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CXCR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur CXCR3

Antigène: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Autre désignation: CXCR3

Sujet: The CXCR3 protein is a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-gamma), CXCL10/IP10 (interferon-gamma-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell alpha-chemoattractant) (reviewed in 1). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration (2). Similar to other chemokine receptors such as CXCR4, CXCR3 has been implicated in several malignancies as a biomarker of tumor behavior as well as a potential therapeutic target (3).

Poids moléculaire: Predicted: 46 kDa

Observed: 43 kDa

ID gène: 2833

NCBI Accession: NP_001136269

UniProt: P49682