UCP1 anticorps (C-Term)

N° du produit ABIN6991968

Cet anticorps anti-UCP1 Polyclonal Lapin (ABIN6991968) détecte spécifiquement UCP1 dans WB, ELISA et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour UCP1 anticorps (C-Term) (ABIN6991968)

Antigène: UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UCP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-UCP1 anticorps

Épitope: C-Term

Specificité: UCP1 antibody is human, mouse and rat reactive.

Purification: UCP1 antibody is affinity chromatography purified via peptide column.

Immunogène: UCP1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human UCP1 (GenBank accession. The immunogen is located within the last 50 amino acids of UCP1.

Isotype: IgG

Information d'application

Indications d'application: UCP1 antibody can be used for detection of UCP1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: UCP1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: UCP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur UCP1

Antigène: UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))

Autre désignation: UCP1

Sujet: The mitochondrial brown fat uncoupling protein 1 (UCP1) is a member of the family of mitochondrial anion carrier proteins (MACP) (1). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells (1). UCP1 is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat (1).

Poids moléculaire: Predicted: 34 kDa

Observed: 35 kDa

ID gène: 7350

NCBI Accession: NP_068605

UniProt: P25874

Pathways: Proton Transport, Brown Fat Cell Differentiation